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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRM2
All Species:
19.39
Human Site:
S246
Identified Species:
35.56
UniProt:
Q14416
Number Species:
12
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14416
NP_000830.2
872
95568
S246
E
K
V
G
R
A
M
S
R
A
A
F
E
G
V
Chimpanzee
Pan troglodytes
A3QNZ8
839
95029
S211
N
W
I
I
V
L
V
S
S
D
T
Y
G
R
D
Rhesus Macaque
Macaca mulatta
A3QP01
839
95041
W203
Q
L
M
L
H
F
R
W
N
W
I
I
V
L
V
Dog
Lupus familis
XP_541867
872
95696
S246
E
K
V
G
R
A
M
S
R
A
A
F
E
G
V
Cat
Felis silvestris
Mouse
Mus musculus
Q14BI2
872
95869
S246
E
K
V
G
R
A
M
S
R
A
A
F
E
G
V
Rat
Rattus norvegicus
P31421
872
95755
S246
E
K
V
G
R
A
M
S
R
A
A
F
E
G
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518731
870
95758
S246
E
K
V
G
R
S
M
S
R
A
A
F
E
G
V
Chicken
Gallus gallus
XP_416842
879
98936
I252
E
K
V
G
R
S
N
I
R
K
S
Y
D
G
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5U9X3
867
97118
D248
A
F
K
A
I
L
P
D
S
L
A
D
Q
Q
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91685
976
108467
D259
E
K
V
P
S
A
A
D
D
K
V
F
D
S
I
Honey Bee
Apis mellifera
NP_001011624
933
103448
D270
V
K
V
P
S
A
A
D
D
R
M
F
D
D
I
Nematode Worm
Caenorhab. elegans
Q09630
999
113258
Q314
E
S
I
N
N
L
V
Q
K
L
Q
P
E
K
N
Sea Urchin
Strong. purpuratus
XP_784936
1474
165598
D820
E
K
I
P
Y
S
P
D
A
M
T
Y
D
I
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
27.6
27.6
98.1
N.A.
97.4
97.8
N.A.
88.3
67.9
N.A.
25.5
N.A.
45.7
47
39.9
32.2
Protein Similarity:
100
46.3
46.3
98.9
N.A.
98.5
98.7
N.A.
92.7
82.2
N.A.
43.8
N.A.
61.7
63.3
55.6
43.4
P-Site Identity:
100
6.6
6.6
100
N.A.
100
100
N.A.
93.3
53.3
N.A.
6.6
N.A.
33.3
26.6
13.3
13.3
P-Site Similarity:
100
26.6
20
100
N.A.
100
100
N.A.
100
80
N.A.
13.3
N.A.
46.6
40
33.3
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
0
47
16
0
8
39
47
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
31
16
8
0
8
31
8
8
% D
% Glu:
70
0
0
0
0
0
0
0
0
0
0
0
47
0
0
% E
% Phe:
0
8
0
0
0
8
0
0
0
0
0
54
0
0
0
% F
% Gly:
0
0
0
47
0
0
0
0
0
0
0
0
8
47
0
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
24
8
8
0
0
8
0
0
8
8
0
8
24
% I
% Lys:
0
70
8
0
0
0
0
0
8
16
0
0
0
8
8
% K
% Leu:
0
8
0
8
0
24
0
0
0
16
0
0
0
8
0
% L
% Met:
0
0
8
0
0
0
39
0
0
8
8
0
0
0
0
% M
% Asn:
8
0
0
8
8
0
8
0
8
0
0
0
0
0
8
% N
% Pro:
0
0
0
24
0
0
16
0
0
0
0
8
0
0
0
% P
% Gln:
8
0
0
0
0
0
0
8
0
0
8
0
8
8
0
% Q
% Arg:
0
0
0
0
47
0
8
0
47
8
0
0
0
8
0
% R
% Ser:
0
8
0
0
16
24
0
47
16
0
8
0
0
8
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
16
0
0
0
0
% T
% Val:
8
0
62
0
8
0
16
0
0
0
8
0
8
0
54
% V
% Trp:
0
8
0
0
0
0
0
8
0
8
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
0
0
24
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _